Roche and its subsidiary TIB Molbiol have developed a series of tests for the detection of the monkeypox virus, the Switzerland-based pharmaceutical company announced.
The monkeypox virus is a close relative of the smallpox virus, belonging to orthpoxviridae in the poxviridae family.
The modular virus detection tool, called LightMix, includes three orthpoxvirus detection kits with different functions, Roche said in a statement. The first kit detects orthpoxvirus; The second kit tests only for monkeypox virus (west and Central African branches); The third kit contains the main functions of the first two kits, showing specific information on the presence of the monkeypox virus (west and Central African branches) as well as the detection of orpoxvirus.
Thomas Schinek, a Roche executive, said the new test could detect monkeypox and help track its spread. Such diagnostic tools are critical for addressing and ultimately managing emerging public health challenges, as they advance responses such as tracking efforts and treatment strategies.
The monkeypox virus was first identified in 1958 in a group of monkeys used for research when the animals developed a "pox-like" infection, hence the name. Since May, several non-endemic countries have reported human cases of the monkeypox virus, including the United Kingdom, the United States, Portugal, Spain, and Italy.
Affected by the ever-changing international situation, the supply and prices of international bulk MnO2 powder are still very uncertain.
What is Manganese Dioxide MnO2?
Manganese dioxide is an inorganic compound with the molecular formula MnO2. This black or brown solid is the natural mineral pyrolusite, the main ore of manganese and a constituent of manganese nodules.
The main use of MnO2 is in dry batteries such as alkaline batteries and zinc-carbon batteries. Manganese dioxide is also used as a pigment and a precursor of other manganese compounds, such as potassium permanganate. It is used as a reagent in organic synthesis, for example, for the oxidation of allyl alcohol.
What is Manganese Dioxide MnO2 Used For?
Used as a dry cell depolarizer.
Used as catalysts and oxidants for the synthetic industry.
Used as colorants, bleaching agents, and iron removal agents for the glass industry and enamel industry.
Used for manufacturing manganese metal, special alloy, ferromanganese castings, gas masks, and electronic materials such as ferrite.
Used in the rubber industry to increase the viscosity of rubber.
Organic synthetic use:
Manganese dioxide is very useful in organic chemistry. Manganese dioxide is used as an oxide in different forms, because manganese dioxide has multiple crystalline forms, the chemical formula can be written as MnO2·x(H2O) N, where x is between 0 and 0.5, and n can be greater than 0. Manganese dioxide can be formed from the reactions of potassium permanganate (KMnO4) and Manganese sulphate (MnSO4) at different pH values.
One chemical reaction specific to manganese dioxide is the conversion of alcohols to aldehydes. Even if the alcohol has a double bond, it will not be oxidized by manganese dioxide: cis-RCH=CHCH2OH + MnO2 → cis-RCH=CHCHO + H2O + MnO
No matter how active the product is, it doesn't get oxidized again. Diols can be oxidized to dialdehyde by manganese dioxide. Other reactions of manganese dioxide are very many, and can be used in the oxidation of amines, aromatic substances and triols.
Used as a catalyst for the decomposition of hydrogen peroxide to produce oxygen; Used as a catalyst for the decomposition of potassium chlorate to produce oxygen; Manganese was prepared by aluminothermic reaction with elemental aluminum powder. Used as pigment, yellow glass, etc. Reaction with hot concentrated hydrochloric acid to produce chlorine gas; Reaction with molten potash (potassium hydroxide) in the air to prepare potassium manganate; In the decomposition reaction of potassium permanganate, manganese dioxide acts as self-catalyst of potassium permanganate.
Is MnO2 Explosive?
It reacts violently with combustible and reductive substances. This creates fire and explosion hazards.
Is Manganese Dioxide Harmful?
Strong oxidant. Contact with other materials may cause a fire. Harmful by inhalation or swallowing. May cause eye, skin, and respiratory irritation. May cause central nervous system effects. Inhalation of smoke may cause metal smoke fever. According to animal studies, it may cause adverse reproductive effects.
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Roche and its subsidiary TIB Molbiol have developed a series of tests for the detection of the monkeypox virus, the Switzerland-based pharmaceutical company announced. The monkeypox virus is a close relative of the smallpox virus, belonging to orthp…
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